Drug Development and Delivery

Creative Biostructure has launched the iEM Platform, a unique integrated platform for electron microscopy (EM) and other microscopy technologies. We focus on various types of materials morphology, chemical components, and characterization, which can play a critical role in drug development and delivery. With the help of our advanced platform and professional experts, biomedical researchers can discover and identify various compounds with medical bearing. Then, these candidate drugs and drug carriers can be designed and used in a wide array of applications. Our services consist of four major sections, including drug discovery, drug development, nanoparticle characterization, and viral vector characterization.

Service Offering

Drug Discovery

In the drug discovery process (from drug target identification to precursor optimization), the three-dimensional (3D) structural information of macromolecular drug targets and their ligands is very important. Structure-based drug discovery technology combines cutting-edge results from multiple disciplines to allow large-scale virtual compound library screening and small molecule structure design. In addition to predicting potential targets, structure-based drug discovery technologies can identify new uses for existing drugs. Our cryo-EM analysis technology is in the leading position worldwide. The high resolution, nearly natural, fully hydrated protein structure provides a breakthrough for structure-based drug discovery and design.

Drug Development

Particle analysis and characterization of APIs, drugs, and excipients are necessary to obtain the highest quality pharmaceutical products. Creative Biostructure is a reliable and professional partner in the drug discovery and development. We are dedicated to providing high-resolution images of a wide array of samples, enabling medical researchers and professionals to obtain higher productivity and better conclusions. Our platform allows researchers to investigate the uniformity, particle size, surface morphology, chemical composition, and contaminants of the drugs.

Characterization of Nanoparticles for Drug Delivery

Characterization and analysis of drug nanoparticles (NPs) for drug delivery is an essential study because NP-based drug delivery opens up a wide scope for various therapeutic drugs to reach human target sites. With the help of our advanced platform, companies and biomedical researchers can investigate nanostructure during formulation, biological transport, and stability assessment. To investigate and characterize various nanoparticles, we are a trusted partner for professionals and researchers.

Viral Vector Characterization

Today, a variety of virus-based drugs are approved and developed worldwide for a wide range of applications, including the treatment of cancer, neurology, metabolic, and muscle diseases. Virus-based gene therapy products will continue to play a key role in pharmaceutical innovation for years to come. However, the inherent complexity of viral vector products, including their physical size, formulation, and vector function, makes their physical and biological properties highly challenging. Based on our integrated microscopy platform, we are able to provide powerful image datasets, quantitative data, and conclusions from the analysis to fully assist viral vector characterization, including adeno-associated virus (AAV) vector, adenovirus vectors, and lentiviral vectors.

The CDB-iEM is an integrated microscopy platform designed to provide a full range of advanced imaging technologies to companies and biomedical researchers worldwide. Please contact us if you would like to have personal expert advice on our microscopy solutions for drug development and delivery.